Mucoadhesive Drug Delivery system. Mucoadhesive multiparticulate system

      Аннотация: Gastrointestinal mucoadhesive drug delivery system targets the drug to its absorption site and maintain the dosage form at that site for an extended period of time. This results in enhanced drug absorption, which will in turn increase the bioavailability of the drug and thus will decrease the dosing frequency and dose related side effects of the drugs. Microparticulate delivery system is preferred over conventional tablet system as it has several advantages like it provides a wider surface area of contact between drug and the absorption site and also controlles the release of drug from the formulation over extended period of time. Thus the potential of above mentioned drug delivery device is promising and may be considered as a novel tool inorder to improve the therapeutic efficacy of various drugs with shorter half life and poor bioavailability.

Ключевые слова: Spray Drying, ., Gastrointestinal, mucoadhesive, Multiparticulate, Beta blocker