Phytochemical Investigations on Sorbus cashmiriana. Isolation, Structure Elucidation, and Biological Evaluation of the chemical constituents

      Аннотация: The aim of the present study is to provide scientific evidence concerned to the medicinal values of the plant Sorbus cashmiriana Hedlund Monog. Phytochemical work on Sorbus cashmiriana has resulted in the isolation of a new cyanogenic glycoside (1) along with eleven known compounds 2-12. The structures of these compounds were characterized by using different spectroscopic techniques, including UV, IR, and 1D-NMR (1H- and 13C-), and 2D-NMR techniques (HMQC, HMBC, COSY, etc.), and mass spectrometry (EI-MS, HR-MS, and FAB-MS). Furthermore, the crude extract, fractions and the isolated compounds of the plant were tested for antibacterial, antifungal, insecticidal, phytotoxic, and brine shrimp lethality activities along with the xanthine-xanthine oxidase and urease inhibition, and superoxide scavenging studies and the results are discussed.

Ключевые слова: Medicinal plants, biological activities, phytochemical investigations, structure elucidation