Pravastatin. Microbial production and biomedical applications

      Аннотация: Hypercholesterolemia, or elevated plasma cholesterol level, has long been recognized as a major risk factor for atherosclerotic disease, and specifically for coronary heart disease. Statins are a group of extremely successful drugs that lower the cholesterol level in the blood. This monograph represents the culmination of several years of research on microbial production of pravastatin and biological effects of this statin compound. Monograph contains a lot of illustrations on topic of interest. It is rich with new ideas and new directions for research on pravastatin as one of the present ‘wonder drugs’. This book could be a valuable reference for scientists and engineers in industrial microbiology, pharmaceutical biotechnology, and biochemical engineering. It could also serve as a reference book for graduate and undergraduate students. In addition, the information in this book could be useful for health professionals.

Ключевые слова: hypercholesterolemia, Microorganisms, Statins, heart attack, pravastatin, Pharmaceuticals, Fermentation, optimization