Noscapine Analogs. Synthesis,Cytotoxic and Pharmacokinetic Studies

      Аннотация: Over the last few years, the cancer has emerged as a leading cause of death. Therefore, all the biomedical students, pharmaceutical companies and reseachers aimed at discovering the drugs which will be more potent and efficacious for the traetment of cancer. In view of above we have considered Noscapine which has been discovered as a safe antitussive agents and binds to tubulin, arrests divinding cells in mitosis and induces apoptosis. This book , therefore, provides an insight regarding the importance of noscapine in cancer studies. We have also provided the information regarding the synthesis , pharmacokinetics and cytotoxicity studies of the analogs of the noscapine.The conclusion from our studies should be especially useful to the professionals in pharmaceutical sciences, biomedical sciences and anyone else who is doing research in the field of noscapine in cancer treatment.

Ключевые слова: anticancer, Noscapine, analogs synthesis, IC50., Pharmacokinetics