Therapeutic Snake Antivenoid. IgG - Production and Quality Assurance

      Аннотация: Therapeutic Snake Antivenoid. This text book is designed to cater the basic needs of the scientists working in the field of Biotechnology, Immunology, Biochemistry, Microbiology and Pharmacology. This book also gives a description of guidelines for the large and small scale production and Quality Assurance of antivenoid immunoglobulins. The down stream processing of F (ab)2 fragments of immunoglobulins and the various quality control in vivo and in vitro techniques of the therapeutic biomolecules are elaborated. The book is compartmented into eight following chapters. 1. Introduction, 2. Characterization of Snake venoms, 3. Detoxification of Snake venom, 4. Production of Snake venoid antisera in small animals, 5. Large Scale production of Snake venoid in Equine, 6. Fractionation of Venoid antisera and in house testing, 7. Symptoms, Treatment and Clinical assessments of Snake veniod antisera, 8. Quality control and Quality assurance of Antivenoid sera.

Ключевые слова: purification, LD50, Cobra, neutralization, Fractination of Plasma (IgG), sterility, Snake venoid, Undue toxicity.