Поиск по каталогу |
(строгое соответствие)
|
- Профессиональная
- Научно-популярная
- Художественная
- Публицистика
- Детская
- Искусство
- Хобби, семья, дом
- Спорт
- Путеводители
- Блокноты, тетради, открытки
Formulation and Evaluation of an In Situ Gel for Ocular Delivery.
В наличии
Местонахождение: Алматы | Состояние экземпляра: новый |
Бумажная
версия
версия
Автор: Sachinkumar Patil,Shitalkumar Patil and Amit Jagdale
ISBN: 9783659461910
Год издания: 2013
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 100
Издательство: LAP LAMBERT Academic Publishing
Цена: 31889 тг
Положить в корзину
Способы доставки в город Алматы * комплектация (срок до отгрузки) не более 2 рабочих дней |
Самовывоз из города Алматы (пункты самовывоза партнёра CDEK) |
Курьерская доставка CDEK из города Москва |
Доставка Почтой России из города Москва |
Аннотация: Norfloxacin ophthalmic solution has been shown to be effective ocular infections and may be used in patients with chronic conjunctivitis or ocular irritation. Norfloxacin in-situ gel was prepared using various concentrations of polymers such as Carbopol-940 (0., 0.2, 0.3 0.4and 0.5% w/v), HPMC- E50LV (1.5 % w/v), HPMC E4M (0.6 %w/v) and HPMC K4M (0.5% w/v) by pH triggered gelling system with an objectives of increasing contact time, achieving controlled release, reduction in frequency of administration and greater therapeutic efficacy of drug. The prepared in-situ gels were then evaluated for their visual appearance, clarity, pH, drug content analysis, in-vitro gelation (Gelling capacity), rheological studies, sterility testing, textureanalysis and in-vitro drug release studies. It is evident from these studies that, formed polymeric in-situ gels had transparent, clear possessing satisfactory gelling capacity. The developed formulation was light yellow in colour, therapeutically efficacious, stable, non irritant with sustained release of drug.
Ключевые слова: in situ gel, Ocular Delivery, anticonjectival drug
Похожие издания
Отрасли знаний: Медицина -> Фармакология и фармацевтика Pallavi Suroshe,Ravi Wanare and Deepak Gadhave Formulation and evaluation of in situ gel for ocular drug system. . 2018 г., 84 стр., мягкий переплет Conjunctivitis is an acute inflammation of the conjunctiva, most commonly due to an allergic reaction or an infection (usually viral, but sometimes bacterial). In situ gel means conversion of sol-to-gel by pH , temperature and ion-sensitivity. The main advantage of in situ gel are increases drug contact time at ocular region sustained drug... | 24061 тг |