Wound Healing Activity of Wedelia trilobata (L.) Leaves.

      Аннотация: Traditional knowledge-driven bioprospecting offers access to multiple targets that can provide a safer and more cost-effective platform for newer scaffolds to facilitate drug discovery. Medicinal herbs have been used since ancient time to heal wounds, skin ulcers, pressure sores, bed sores and burns. More than 80% of the world’s population still relies upon traditional medicines for varied skin diseases. The presence of various health sustaining constituents in plants has activated scientists to examine these plants with a view to determine potential wound healing properties. The medicinal value of these plants lies in their bioactive components that produce exact physiological actions on the human body. These constituents include various members of chemical families like alkaloids, essential oils, ?avonoids, tannins, terpenoids, saponins, and phenolic compounds. Herbal medicines used for wound management involve disinfection, debridement and even by just providing a moist environment that will encourage natural healing processes.

Ключевые слова: wound healing, Fibroblast cells, Keratinocytes, Wedelia trilobata, grandiflorenic acid