Gardenins - The Flavonoids. Derivatization, Characterization and Screening of Flavones

      Аннотация: The book gives us information about the flavones, Gardenin A and B of Dikamali gum-resin (Gardenia gummifera Linn.). It is a handy tool which provides the step by step and elaborative description about experimental methods i.e. Extraction, Chromatographic fractionation, Isolation, Purification, Characterization, Structural determination, Invitro Pharmacological and Mircobiological screening. Research work on Dikamali gum-resin was initiated by keeping the views of traditional claims. The isolated flavones and their derivatives were characterized by spectral methods and screened for their antibacterial, anticholinergic and antihistaminic activity. Derivatization of Gardenin A and B led to the exploration of newer analogues, Gardenin A methyl ether and Gardenin B benzoate that are potent antihistamines. This book would push open a new window for the Pharmaceutical scientists who strive to gift mankind with life saving drugs from the mother nature.

Ключевые слова: antibacterial, Antihistaminic, Cholinergic, Anticholinergic, Gardenin A, Gardenin B, Dikamali Gum Resin, Gardenia gummifera Linn.