Taurine as Hypocholesterolemic agent. The role of Taurine on Some Physiological and Histological Changes in Hypercholesterolemic Male Rats

      Аннотация: Recently the attention has increased in the use of food additives to prevent diseases, especially lifestyle related diseases such as metabolic syndrome. Taurine is one of the most important of these additives which has received wide attention in the recent year and due to properties which taurine has. Taurine, the 2-aminoethanesulfonic acid, which is conditionally essential nutrient, which is synthesis from amino acids cysteine and methionine. It is the major free amino acid that is found in many animal tissues including the brain, retina, myocardium, skeletal muscle, liver, platelets, and leukocyte.The physiological functions of taurine include Its works as an inhibitory neurotransmitter and contributed to brain and retinal development , cell membrane stabilization , detoxification, its conjugation with the bile acid and fat metabolism, antioxidant and protecting blood vessels and blood cells from the oxidative damage, and controlling osmoregulation through membranes transport.Despite the progress in taurine research in the last 30 years, the biological and physiological function of taurine still needs more investigation. Therefore, the present study introduce to you.

Ключевые слова: High Cholesterol diet, Taurine, Physiological, histopathological parameters