Design and Development of Novel Anticoagulant Agents. Development of anticoagulant

      Аннотация: "Design and Development of Novel Anticoagulant Agents" is a new book which describes the process of drug design and development of new potent and less toxic anticoagulant drug like candidate. Both Drug design and synthetic aspects of these designed leads are described in this book. The Computer aided drug design aspect and various methods used in in-silico drug design process has been covered under this book. Various methods of bio-activity evaluation of anticoagulant agents also described in detail. In-silico ADMET prediction software's there accessibility, various database used for prediction are cover under this book. In-silico rational design, development, optimization and synthesis of novel anticoagulant drug like candidate developed having specific interactions with clotting factor IXa and Xa described in detail. The book is expected to serve the needs of Pharmaceutical Sciences student in particular and also researchers of other related profession such as Medicine.

Ключевые слова: Anticoagulant, Drug design and Development, Factor IXa and Xa