Glucocorticoid-metabolic theory of diabetes mellitus type 2. Biochemical and pathophysiological aspects

      Аннотация: This monograph considers well-known biochemical and pathophysiological data in terms of diabetes mellitus type 2 as a disease characterized primarily violation of energy metabolism of cells in which the main actor and conductor of «pathogenic ensemble» is endogenous cortisol. From this perspective, explains all the manifestations of diabetes mellitus type 2 and mechanisms for the development of complications. The new theory is based on fundamental universally recognized facts and does not contradict the existing experimental and clinical data.

Ключевые слова: etiology, glucocorticoids, Insulin resistance, pathogenesis, diabetes mellitus II type, diabetes mellitus 2 type