Macrophages phenotype and function in primary lung cancer. Lung cancer, Tumour microenvironment, Biomarkers

      Аннотация: Lung cancer is one of the most commonly reported cancers, and is known to be associated with a poor prognosis. The role of macrophages in lung cancer, including alveolar macrophages (AMs), tumour-associated macrophages (TAMs) and monocytes, is multifaceted and the literature shows conflicting roles. This book is aiming to increase the knowledge regarding the characterization of the M1(classically activated) and M2 (alternatively activated) macrophage subsets in primary lung cancer and to demonstrate new potential biomarkers. This book would be useful to the people who are interested in research areas regarding lung cancer, molecular oncology, immunology and modern immunohistochemistry.

Ключевые слова: Flow Cytometry, immunohistochemistry, lung cancer, macrophages, Proteomics