Поиск по каталогу |
(строгое соответствие)
|
- Профессиональная
- Научно-популярная
- Художественная
- Публицистика
- Детская
- Искусство
- Хобби, семья, дом
- Спорт
- Путеводители
- Блокноты, тетради, открытки
Stem cells. In vitro neurogenesis of human and rat bone marrow derived mesenchymal stem cells
В наличии
Местонахождение: Алматы | Состояние экземпляра: новый |
Бумажная
версия
версия
Автор: Sarah Al-Sawalha,Jabbar Yanzeel and Abdul Majeed Hammadi
ISBN: 9783659858338
Год издания: 2016
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 144
Издательство: LAP LAMBERT Academic Publishing
Цена: 39591 тг
Положить в корзину
Способы доставки в город Алматы * комплектация (срок до отгрузки) не более 2 рабочих дней |
Самовывоз из города Алматы (пункты самовывоза партнёра CDEK) |
Курьерская доставка CDEK из города Москва |
Доставка Почтой России из города Москва |
Аннотация: This study aimed to investigate the ability of mesenchymal stem cells derived from bone marrow of human and rat to transdifferentiate into functional neural like cells. A study was made on two different models (human and rat) using two different techniques (direct plating, and density gradient method) respectively. Immunophenotypic analysis demonstrated that human and rat BM-MSCs at passage three uniformly positive for CD44 sub-population. However, MSCs were always found to be negative for heamatopoietic specific markers CD34. To explore the possibility of BM-MSCs in vitro transdifferentiation, the expanded MSCs from third passage were allowed to reach 80% confluence and induced to differentiate into neuron like cells by an enhanced three-step protocol. The identity of the NLCs were illustrated by the analysis of morphology using immunocytochemistry.
Ключевые слова: Bone marrow, Stem cells, neurogenisis
Похожие издания
Отрасли знаний: Медицина Judith Buddensiek Influence of Cerebrospinal fluid on the behaviour of neural stem cells. An in vitro study. 2012 г., 56 стр., мягкий переплет Neurodegenerative disorders such as Huntington’s disease, Amyotrophic lateral sclerosis, Alzheimer’s disease and Parkinson’s disease are characterized by a progressive loss of structure or function of neurons or glial cells in the brain or spinal cord. Thus, the prospect of replacing the missing or damaged nerve tissue is a very attractive... | 32237 тг |