Structural Biology Of CFTR. Investigating of CFTR characterizations using Bio-molecular techniques

      Аннотация: The cystic fibrosis transmembrane conductance regulator (CFTR) is a transmembrane protein that functions as an ion channel. Mutations in this protein cause Cystic Fibrosis. For this reason, it is important to study the structure and function of CFTR. In this book, constructs of CFTR (C-terminii), a CFTR-interacting protein and full-length CFTR will be investigated in terms of DNA cloning, expression and purification for structural and functional studies.

Ключевые слова: DNA cloning, electron microscopy, structural biology, protein expression and purification