Insights into Pathways Leading to Diabetes Mellitus and Complications.

      Аннотация: Diabetes mellitus is a group of common metabolic disorders that share the common phenotype of elevated glucose levels. It is attributed to one of the most prevalent disorders in the modern world and is multi-factorial in progression. The long term prevalence of diabetes leads to various microvascular and macrovascular complications that impose a major harbinger to the human life. This book will provide an up to date and complete information on the hidden mechanisms that leads to the progression of diabetes ultimately disposing to life threatening complications.

Ключевые слова: Insulin, beta-cells, glucose tolerance, polyol pathway, advanced glycation end-products