Influence of Hydrophobic Polymer on Drug Release: A Case Study.

      Аннотация: The study is aimed to develop extended release tablet using hot melt granulation method which will include hydrophobic polymer that will form hydrophobic matrices which will retard release of drug for extended period of time. The optimization of polymer concentration, on the basis of experiments and statistical analysis of the results will provide an efficient prediction of the optimal composition. Hence, a factorial design will be employed for the preparation of the tablets possessing optimal characteristics.

Ключевые слова: Extended release tablet, Hydrophobic polemer, melt granulation