DNA interaction and antioxidant of some Amino Acid Imine Chelates. Physicochemichal properties, DNA interaction, antiviral and antioxidant activities of some Amino Acid Imine Chelates

      Аннотация: Amino acids contribute the building blocks of proteins and are chemical species indispensable for performing a huge number of biological functions, as exemplified by the role of enzymes. Over the years and till now, the study on imine ligands is of keen attention since they are being considered as the most privileged ligands in the coordination chemistry due to their ease of preparation through the simple condensation reaction between primary amines and carbonyl compounds. Moreover, when such imine ligands are coordinated with metal ions, their applications are found to be enhanced. For instance, the applicability of imine chelates extends to diverse fields such as catalysis, sensors, luminescent and nonlinear optical materials. It is worth mentioning that, the imine group of Schiff base ligands leads to the enormous biological activities including antitumor, antibacterial, antifungal and herbicidal activities.

Ключевые слова: Amino acid, antibacterial, antifungal, antioxidant., Antiviral, gel electrophoresis, Schiff base, TEM, TGA, Thermodynamic parameters, binary complexes, ternary complexes, CT-DNA binding