Cardio-protective Role of Cilostazol & Milrinone. Experiment, Observation & Results of Cilostazol, Milrinone and their combination effect on ISO induced MI in wistar rats

      Аннотация: Healthy human life is always cardinal for human being starting from his birth to the end life. Myocardial infarctions produce clinical symptoms that include intense chest pain that may radiate into the neck, jaw or arms, a sense of substernal heaviness, squeezing or pressure, dyspnea, fatigue, syncope, diaphoresis, anxiety, sleeplessness, hypertension or hypotension, tachycardia and arrhythmias. This book includes study of path-physiology, symptoms, complications, diagnostic procedures for myocardial infarction with diagrammatic illustrations. Cilostazol and Milrinone forms the basis of treatment of various heart diseases but this book gives an pre-clinical experimental approach for treating myocardial infarction which is induced by isoproterenol in wistar rats and then subjected to the treatment with cilostazol, milrinone and their combination doses. This book will be of great interest for the cardiologist, physicians, academicians, professors, medical and paramedical students, and will form the basis of authentication for various pre-clinical and clinical studies as these two drugs can be used for treating myocardial infarction within humans.

Ключевые слова: Isoproterenol, myocardial infarction, pathophysiology, Cardio-protective, Cilostazol, Milrinone, Phosphodiesterase Inhibitors