Pioglitazone loaded SMEDDS: State of the Art.

      Аннотация: This book represents the systematic exposition of enhancement in therapeutic potential of anti-diabetic agent (Pioglitazone) through Self microemulsifying drug delivery systems (SMEDDS). Introductory part consist of latest world scenario of one of the most prevailing disease in today's era i.e. diabetes, followed by research work consisting formulation, development and characterization of Pioglitazone loaded SMEDDS. Despite of having good bioavailability, poor aqueous solubility and slow dissolution rate renders negative impact on sub-therapeutic plasma levels leading to Pioglitazone's therapeutic failure. A crucial feature of this book is to present that how delivery of a poorly aqueous soluble can be enhanced through formulating it in the form of SMEDDS. This book will definitely assist various formulation scientists, researchers etc working in the field of oral bioavailability enhancement of poorly aqueous soluble agents.

Ключевые слова: Diabetes; Pioglitazone; Bioavailability; poor Solubility; SMEDDS; Anti-Diabetics.