Optimization of Stability Indicating methods for some formulation.

      Аннотация: The purpose of this book is to review of stress testing of Pharmaceutical formulation.Stability study applied for multi-dose products to ensure that the product preserves its quality parameters after opening during use period. The physical, chemical and microbial properties of the product susceptible to change during storage should be determined over the period of the proposed in use shelf-life; and for liquids, preservatives, per content and effectiveness, need to be evaluated in this study Forced degradation studies also provide invaluable insight in investigating degradation products. The use of properly designed and executed forced degradation study will generate a representative sample that will in turn help to develop stability-indicating HPLC method.

Ключевые слова: HPLC, Stability, validation