Herbal Oil Supplement and Diet with Hot Nature for Multiple Sclerosis.

      Аннотация: Multiple sclerosis (MS), ensuring demyelization results in physical disability, is the most chronic and inflammatory disorder. Because of limited efficacy and adverse side effects of the current treatments, identifying novel therapeutic and protective agents is important. For many years, it has suspected that the risk of developing MS might be associated with increased dietary intake of saturated fatty acids and consumption Cold nature foods. This study aimed to assess the potential therapeutic and protective effects of hemp seed and evening primrose oils as well as Hot-nature dietary intervention on mild MS patients. This study suggests that co-supplemented herbal oils with Hot nature diet can have beneficial effects in reversing the signs and improve clinical outcome in RRMS patients which were confirmed by immunological and biochemical findings. This intervention causes an increase PUFAs in MS patients and improvement in the erythrocyte membrane fatty acids composition and it could be an indication of restored plasma stores, and a reflection of disease severity reduction.

Ключевые слова: inflammation, liver enzymes, Phospholipase A2, PUFA, Cell membrane fluidity, Delta-6-desaturase (FADS2), Evening primrose oil (Oenothera biennis L), Expanded disability status scale (EDSS), Hemp seed oil (Cannabis sativa L), Hot-nature diet, Mizadj, Relapsing Remitting Multiple sclerosis (RRMS).