Perioceutics - an adjunct to periodontal therapy.

      Аннотация: Perioceutics or the use of the pharmacological agents specifically developed to manage periodontitis is an interesting and emerging aid in the management of periodontal diseases along with mechanical debridement .The purpose of host modulatory agents, which is an imperative part of perioceutic, is to restore the balance between, on the one hand, pro inflammatory mediators and destructive enzymes, and on the other hand, anti inflammatory mediators and enzyme.Host modulatory therapy (HMT) is a treatment concept that aims to reduce tissue destruction and stabilize or even regenerate the periodontium by modifying or down regulating destructive aspects of the host response and up regulating protective or regenerative responses. This paper review the Host Modulatory Therapy which in future will be the effective tool dental practitioners when used as adjunct to mechanical therapy in treating periodontal diseases Interest in the potential application of HMTs in treating periodontitis has been driven by improved understanding of periodontal pathogenesis and awareness of the importance of the host response in disease susceptibility and progression.

Ключевые слова: host modulation, Periodontal disease, Non-steroidal inflammatory drugs, Bisphophonates, Sub-antimicrobial dose Doxycycline, Perioceutics