The pathochemical mechanisms of action of sodium fluoride on the body.

      Аннотация: The monograph shows the effect on the body of a chemical substance - sodium fluoride in very small concentrations and the role of regulatory mechanisms in the development of damage to hepatocytes and the brain in the dynamics of intoxication. Sodium fluoride is found in everyday human life as a part of underground (drinking water), in chemical production as a catalyst for chemical processes, for the strength of dental prosthetic materials, in toothpaste, as part of polyethylene food packaging (for example, a lid for yogurt). Important correction of metabolic processes aimed at neutralization and elimination of toxic products, which provides a high-quality diet containing substrates for the antioxidant enzymes of the body. The monograph contains 41 pages, 5 figures and 2 tables. Recommended for therapists, pediatricians, biochemists, biophysicists, gerontologists.

Ключевые слова: Reduced glutathione, sodium fluoride, hepatocyte's membrane, phospholipid composition, Wistar rats' population, liver detoxication system, glutathione system of enzyme's activity, liver homogenate, active liver microsomes of hepatocytes, liver rats, free radical processes, lipid peroxidation