Drug Targeting. Targeted drug delivery to cells and organs

      Аннотация: Conventional drug therapies suffer from several limitations most prominently the pharmacokinetic alterations in biological system which results in decreased bioavailability at the desired site of action. Furthermore, the undesired distribution, biotransformation and elimination lead to cause serious toxicities and sub-maximal therapeutic efficacy. The concept of Targeted Drug Delivery Systems (TDDS) thus emerged to limit these consequences and exaggerate the therapeutic value of the medicine.

Ключевые слова: carriers, Microparticles, nanocarriers, targeted drug delivery, Site specific drug action, Vesicular carrier system, Cells as carrier system