Cardiovascular Protection with Adenosine Combined Antioxidants.

      Аннотация: This research designed and synthesized novel dual action cardio-protective agents combining with nitroxides possessing antioxidant properties. The work resulted in the discovery of a new generation of chemical compounds which can act on more than one targeted disease. This new generation multi-targeted drug compounds can have benefits in reducing toxicity and side effects. The synthesized drug compounds could potentially act as effective preventive treatments for inflammatory diseases and also provide cardiovascular protection.

Ключевые слова: Adenosine, antioxidants, Chemistry, free radicals, Ischaemia, oxidative stress, Synthesis, adenosine receptors, allosteric modulator, nitroxides, cardio-protection, dual-acting drug.