Formulation & Development of Floating Drug Delivery System. Formulation, Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Anti-platelet Drug

      Аннотация: From above experimental findings it can be concluded that: • Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. • The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. • The mechanism of drug release was found to be matrix diffusion controlled. • Formulations showed satisfactory results from Stability studies. • Further in-vivo investigations are necessary to correlate in-vitro data.

Ключевые слова: development, evaluation, Floating Drug delivery System, formulation, Gastro Retentive, Anti platelets