Lab Manual of Medicinal Chemistry. B.Pharmacy and Pharm D students

      Аннотация: The book contains a comprehensive list of laboratory equipment and safety measures to be taken in the chemistry lab. Targeted mainly to B. Pharmacy students, this book will also be useful for Pharm D as well as M. Pharmacy pharmaceutical chemistry students. The experiments described are very simple to carry out and does not require any special equipments. It features a large number of official drugs synthesis, assay and determination of partition coefficient. Simple methods of preparation of drugs and the methods to calculate their percentage yields were described. The methods to determine the amount of the drug present in the marketed samples was also described. IR spectra of some official compounds along with the ranges of the functional groups were described. Salient features of this book • Safety measures to be taken in a chemistry lab were explained clearly. • Role of reagents, chemicals and hazards associated are highlighted. • Procedures followed by calculations of the methods described with very simple language. • Reactions involved in various synthetic methods, assays are cleared designed. • For the calculation of percentage yields, the formulas and mol. weights included.

Ключевые слова: medicinal chemistry, official drugs, Synthesis, Assay, Paracetamol, Partition coefficient, Monograph analysis, IR spectra.