The Futural Pharmacotherapy of Cancer: Preliminary Grounded Study.

      Аннотация: Cancer is not a single disease; rather, it is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. Cancer cells do not respond to the normal processes that regulate cell growth, proliferation, and survival. They do not carry out the physiologic functions of their normal differentiated counterparts. Cancer chemoprevention focuses on suppressing or reversing carcinogenesis in the early phases and preventing the development of invasive cancer. Surgery is the oldest modality available to treat patients with cancer. Radiation therapy can be used to eradicate localized tumor masses. In spite of surgery, radiation and chemotherapy, the survival of cancer patients remains low. Thus, novel therapeutic strategies are needed. It is most likely that the pharmacologic use of chemotherapy is to be radically changed. The change will arise from better understanding of the biological factors and signaling pathways. In other words, the need is to change from the sole dependence on chemotherapy against cancer cells to pharmacotherapeutic management of the processes that ends in stimulating proliferation of cancer.

Ключевые слова: Cancer, Pharmacotherapy, Cellular basis, tumor growth, surgery, Radiation, Chemotherapy, immunity, Early reactions, Delayed Reactions, Metabolism, glutamate, nicotine, Stress, depression