Controlled Release Programmed Antihypertensive Agents. A Research Study

      Аннотация: This book enlightens the formulation designing, dissolution profile, mathematical modeling, comparison of dissolution profile, pharmacokinetic parameters and in vivo bioavailability parameters. Controlled release delivery system provides a uniform concentration or amount of the drug at the absorption site. We have developed controlled release of recent drugs targeting the uniform release for 12 hrs with Azilsartan, Nimodipine and Isradipine to achieve the reduced fluctuations in drug release and maintenance of plasma drug concentration within an optimal therapeutic range for prolonged duration of treatment with maximum efficiency-dose relationship with economical means of less drug utilized compared to conventional dosage form and reduced adverse effects and minimizing drug accumulation with chronic dosing and economy to enhanced therapeutic benefits and reduced side effects.

Ключевые слова: pharmaceutics, Nimodipine, Azilsartan, Isradipine