Evaluation of the Curative Probability of Bioactive Metabolites. From Endophytic Fungi Isolated from Some Medicinal Plants against Paracetamol-Induced Liver Injury in Mice

      Аннотация: Medicinal plants had been used to isolate and characterize directly the bioactive metabolites. However, the discovery of fungal endophytes inside these plants with capacity to produce the same compounds shifted the focus of new drug sources from plants to fungi. Bioactive natural products from endophytic fungi, isolated from different plant species, are attracting considerable attention from natural product chemists and biologists alike which is clearly depicted by the steady increase of publications devoted to this topic during the recent years. This study highlighted the biochemical potential of endophytic fungi with focus on detection of the curative probability of their bioactive metabolites against paracetamol-induced liver injury in mice.

Ключевые слова: Endophytic Fungi, Curative Probability, liver, mice, Medicinal Plants, Egypt, Paracetamol-Induced Liver Injury