Potential Resistance By Cancer Cells For Multi-Drugs.

      Аннотация: Cancer is a dreadful disease in which the abnormal cells proliferate without control and invade other parts of the body resulting in tumour. Causes for cancer includes tobacco use, excess body weight, inherited genetic mutations, hormones, immune condition, etc. According to the World Health Organization’s (WHO) finding, it is expected that annual cancer cases will rise from 14 million in 2012 to 22 within the next two decades. This is a real alarm to the society and gives us a challenging opportunity to break the threat. Despite having treatment for cancer the rate of success is less. The reason is the cancer cells develop resistance for the treatment and regenerate their properties. Therefore this book provides information regarding their resistance for the treatment along with data about few types of cancers and their strategies to overcome treatment. Different types of transporters which are responsible for the resistance of cancer cells during treatment are mentioned. Few are ABC transporters, P-gp, Pten etc. Many drugs with capacity to overcome resistance are listed and included. Cancer cells adapt instantly for every condition and strategies of cancer cells are discussed.

Ключевые слова: Multi Drug Resistance, Cancer, P-gp, ABC transporters, Chemotherapy