Inflammatory genes and Lung cancer.

      Аннотация: Cancer-related inflammation remains a significant challenge to healthcare providers, as well as to investigators studying the basic mechanisms underlying tumorigenesis. Largely because the pathogenesis of inflammation-associated cancer is incompletely understood, there are currently limited therapeutic techniques for modifying cancers that occur in the setting of chronic inflammation. The accumulating evidence links a wide variety of chronic inflammatory conditions to diverse groups of cancers including lung cancer, providing firm support for the role of inflammation associated cancer as an important event in the pathogenesis of cancer. It may even be the seventh hallmark of cancer, as suggested by Mantovani et al., 2009.

Ключевые слова: lung cancer, Inflammatory genes, Polymorphism, mRNA expression, protein expression