Salivary Biomarkers In Early Childhood Caries.

      Аннотация: Early Childhood Caries (ECC) is a severe and early form of the carious disease that can compromise child’s oral and systemic health. Despite significant efforts identification of children at risk for ECC before the onset of cavitation remains challenging. As teeth are bathed in saliva constantly, the constituents and properties of this oral ?uid play an essential role in the occurrence and progression of oral diseases including dental caries. Thus, it can be a promising tool in early identification thereby preventing further progression of caries in children. This treatise throw light on the current knowledge and utilisation of salivary biomarkers in terms of its predictive potential for ECC. Some of the promising biomarkers identified include the microbiological species, electrolytes in saliva, antibodies, inflammatory mediators, glucosyltransferase and physical characteristics of saliva. Utilisation of these biomarkers in clinical practice might help the clinicians in improving the oral health status of the child.

Ключевые слова: biomarker, diagnosis, Early childhood caries, Predictor, Saliva