Design of Extended Release Matrix Tablet of Tramadol Hydrochloride.

      Аннотация: This study of oral sustained drug delivery system is to achieve a prolonged therapeutic effect by continuously releasing medicament over an extended period of time after administration of a single dose. Sustained release constitutes any dosage form that provides medication over an extended time period. In general, the sustained release dosage form is to maintain therapeutic blood or tissue level of drug for a prolonged period usually accomplished by attempting slow first order fashion.

Ключевые слова: Extended Release Matrix Tablet, Tramadol Hydrochloride, Hydrophobic and Hydrophilic Polymer, Pharmacokinetic and Pharmacodynamics, Release Kinetic