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Toll Like Receptors. Structure and Function
В наличии
Местонахождение: Алматы | Состояние экземпляра: новый |
Бумажная
версия
версия
Автор: Alyaa Farid
ISBN: 9786139584017
Год издания: 2019
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 100
Издательство: LAP LAMBERT Academic Publishing
Цена: 31889 тг
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Аннотация: Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single, membrane-spanning, non- catalytic receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes. Once these microbes have breached physical barriers such as the skin or intestinal tract mucosa, they are recognized by TLRs, which activate immune cell responses. The TLRs include: TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and TLR13, though the last three are not found in humans. TLR's received their name from their similarity to the protein coded by the toll gene identified in Drosophila in 1985 by Christiane N?sslein-Volhard and Eric Wieschaus.
Ключевые слова: TLR1, TLR9, toll like receptors, proteins, Innate Immune System
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