Target genes expression biomarkers in Egyptian bladder cancer patients. Target genes expression biomarkers in Egyptian bladder cancer patients

      Аннотация: Bladder cancer (BC) is a common urologic cancer. Early diagnosis of bladder cancer is critical to improving patient outcomes. Researchers have begun a search for an appropriate marker suitable for the screening of the bladder cancer, which should be specific, sensitive, reproducible, non-invasive and at an acceptable cost. The aim of this study was to use a reverse-transcriptase polymerase chain (RT-PCR) assay for the detection of the genes that are over expressed in the peripheral blood and tissue samples of bladder cancer and compared to normal bladder tissues and blood, One hundred sixty individuals were included in this study and divided into two groups; group I : included eighty patients with bladder cancer were studied in both bladder tissue biopsies and blood sample The present study identified some genes that can be used as molecular biomarkers or target genes in Egyptian bladder cancer patients.

Ключевые слова: Biochemistry, bladder, cancer, genes