Formulation and Development of Microballoons For Hypertension. Development And Optimization of An Antihypertensive Formulation With Losartan Potassium

      Аннотация: Objective of the present investigation was to formulate and develop hollow microspheres of Losartan potassium.It also referred to as high blood pressure, under a condition in which the arteries have persistently elevated blood pressure but also maintain the therapeutic effect for longer period of time.It was belongs to the class III of BCS exhibiting high solubility and low permeability. Hence, enhanced gastric retention time of drug to controlled release dosage form will increase its absorption.The microballoons can act as potential tool in the form of novel drug delivery system against hypertension.

Ключевые слова: Losartan Potassium, Emulsion-solvent diffusion technique, Hollow microspheres, Angiotension II receptor blockers