Поиск по каталогу |
(строгое соответствие)
|
- Профессиональная
- Научно-популярная
- Художественная
- Публицистика
- Детская
- Искусство
- Хобби, семья, дом
- Спорт
- Путеводители
- Блокноты, тетради, открытки
The world of microRNA-377 and multiple sclerosis. Targeting miRNA in multiple sclerosis
В наличии
Местонахождение: Алматы | Состояние экземпляра: новый |
Бумажная
версия
версия
Автор: Majid Amini Khorasgani,Mohammad Hedayati and Parisa Eyvazi
ISBN: 9786200563651
Год издания: 2020
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 56
Издательство: LAP LAMBERT Academic Publishing
Цена: 23066 тг
Положить в корзину
Способы доставки в город Алматы * комплектация (срок до отгрузки) не более 2 рабочих дней |
Самовывоз из города Алматы (пункты самовывоза партнёра CDEK) |
Курьерская доставка CDEK из города Москва |
Доставка Почтой России из города Москва |
Аннотация: One of the most recent studies in genetics has examined the role of microRNAs as biological markers for the diagnosis of multiple sclerosis. There are small and large plaques in the white matter of the brain and spinal cord. miR377-3p, formerly called has-miR-377-3p, is located in the chromosomal region 32q14 and is in the SOD gene. SOD (dismutase superoxide dismutase) is a gene present in the chromosomal region 22q21 and the protein encoded by this gene is the enzyme superoxide dismutase. The aim of this study was to investigate the expression of miR-377 in patients with RRMS (recurrent multiple sclerosis) and healthy individuals who had no history of autoimmune or inflammatory disease. According to the results, miR-377-3p expression was higher in patients than healthy subjects (P = 0.036) and the sensitivity and diagnostic value of miRNA were equal to 0.80 AUC and the results were in accordance with previous studies and miR-377-3p May It can be used as a trademark to diagnose multiple sclerosis.
Ключевые слова: Multiple Sclerosis, RRMS, miR-377-3p, SOD Gene