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Optimization of Formulation. Preparation of Optimized System of Bupropion Hydrochloride Using Formulation by Design
В наличии
Местонахождение: Алматы | Состояние экземпляра: новый |
Бумажная
версия
версия
Автор: Aparna Gupta and Lalit Singh
ISBN: 9786202566025
Год издания: 2020
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 92
Издательство: LAP LAMBERT Academic Publishing
Цена: 31605 тг
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Аннотация: This book includes certain important aspects related to a drug and the optimization of its formulation. The studied drug , i.e. Bupropion Hydrochloride is having potential to act against the depression of youngsters (Major Depressive Disorder) and also helps in cessation of smoking. So, for the enhancement of activity of drug inside the body, a desirable sustained release formulation is prepared which is able to release maximum amount of drug within 12 hrs. This will enhance the patient compliance, as people undergoing with the depression will obtain the drug with sustain release without the repetition of dosing of Bupropion. So, to prepare an optimized formulation of drug, one of the relevant technique of Design of Experiment (DoE) is utilized which is Formulation by Design (FbD). This techniques helped to design the best formulation by taking optimum concentration of chosen dependent and independent variables.
Ключевые слова: Bupropion Hydrochloride, sustained release, Depression of youth, FBD