DEVELOPMENT OF AQUEOUS POLYMERIC DISPERSION'S OF PHARM. DOSAGE FORM. Aqueous Polymeric Dispersion, Eudragit RS & S 100, FT-IR Spectroscopy, DSC Plasticizer and Colon Specific Drug Delivery

      Аннотация: In the present research work, The development of Aqueous Polymeric Dispersions (APD) of four different Eudragit polymers Viz. Eudragit RS PO, Eudragit RL PO, Eudragit S 100 & Eudragit E PO in different concentrations (%w/v) were developed by using emulsification solvent evaporation technology in three following steps:-A.) Development of Aqueous Polymeric Dispersion B.) Development of Polymeric films of optimized Aqueous Polymeric Dispersions C.) Performance Characterization of developed Freeze-Dried Aqueous Polymeric Dispersions The purpose is to replace an organic solvent by aqueous solvent in order to achieve conferring benefits over Organic solvents for different aqueous insoluble polymers in pharmaceutical industries including: Cost reduction Non-toxicity Ecological benefits Manufacturing safety Ease of availability

Ключевые слова: Aqueous Polymeric Dispersion, Eudragit RS & S 100, FT-IR spectroscopy, DSC