USE OF TRANEXAMIC ACID IN TOTAL KNEE ARTHROPLASTY. COMPARISON OF EFFICACY OF INTRA-ARTICULAR AND INTRAVENOUS ROUTE OF ADMINISTRATION OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS IN TOTAL KNEE ARTHROPLASTY

      Аннотация: BackgroundThe antifibrinolytic tranexamic acid reduces surgical blood loss, but studies have not identified an ideal route of administration.We tried to identify whether intra-articular route of administration of tranexamic acid is superior to its intravenous route of administration in reducing blood loss in post-operative period, number of transfusion units and complications e.g. thromboembolic phenomenon and DVT.We prospectively compared the two routes of administration (I/A and I/V) in a study population of 28 patients. In all the patients staged bilateral TKA was performed, one side receiving tranexamic acid I/A and the other I/V.

Ключевые слова: TRANEXAMIC ACID, Total Knee Arthroplasty