Formulation & Evaluation of Self Micro Emulsifying Drug Delivery. Self Micro Emulsifying Drug Delivery System For an antidepressant Drug to increase bioavailability

      Аннотация: Self micro emulsifying drug delivery system (SMEDDS) is well known for its potential as alternative strategy for delivery of hydrophobic drugs, which are associated with poor water solubility and low oral bioavailability. In the present investigation, self micro emulsifying drug delivery system of Lurasidone HCl was formulated and evaluated for its in-vitro and in-vivo performance and our study revealed that the self micro emulsifying formulation of Lurasidone HCl can be successfully developed as a possible alternative to conventional oral formulations.

Ключевые слова: SMEDDS, Self micro emulsifying drug delivery system, bioavailability, antidepressant