Formulation of Sustain Release Matrix Tablet of Antiviral drug.

      Аннотация: The present study includes the formulation and evaluation of sustained release matrix tablet of Antiviral drug. For this study Acyclovir selected as model drug. For this study using natural polymer. To improve matrix performance and release characteristics, a water soluble hydrophilic additive like lactose Mg stearate was added. This study deals with the investigations carried out with the objective of developing oral sustained release formulations through matrix tablets for the widely used Antiviral drug Acyclovir using natural gum as Taro gum and evaluation of their sustained release potential. Compatibility study of drug and polymer was conducted by employing FTIR Spectral. As the identical principal peaks were observed in all the cases, hence it shall be confirmed that interactions do not exist between the drug and polymer. The sustained release matrix tablet prepared by wet granulation technique using different proportions of natural polysaccharides.

Ключевые слова: sustained release, SUSTAINED ACTION, prolonged action antiviral drug, Natual polymer