Seroprevalence of HBV/HCV-HIV Co-infections and outcome follow up of HAART in HIV Patients. In Kumba Health District , South West Region of Cameroon

      Аннотация: Hepatitis B (HBV) and C (HCV) are two among the numerous forms of infections whose clinical degeneration, morbidity-mortality and low immune responsiveness in people living with human immuodeficiency virus (HIV) are highly evident. The aim of this study was to establish the prevalence of hepatitis B surface antigen (HBsAg) and hepatitis C antibody (HCVAb) among HIV-infected individuals, treatment outcomes and identified tha associated risk factors in Kumba Health, in the South West Region of Cameroon.We performed a systematic screening using RDT for HBsAg (hepatitis B surface antigent) and HCVAb (hepatitis C virus antibody) among 299 HIV-positive patients enrolled at Kumba District hospital, CMA Kumba Town hospital and Banga-Bakundu Apostolic Hospital in Kumba Health District, after which positive results for HBsAg and HCVAb were further confirmed by the ELISA test and the prevalence, treatment outcomes and possible risk factors determined. A total of 52 HIV patients, 36 HIV/HBV and 12 HIV/HCV patients were then involved in the prospective cohort study for 24 months follow up. We performed CD4 counts, viral load test, analyzed ALAT/ASAT, albumin, bilirubine, creatinine.

Ключевые слова: HIV, Hepatitis B and C, Co-infection, Prevalence, risk factors, immune response, Kumba Health District.