Quantitative Structure Activity Relationships Study of APIQs. QSAR study of cytotoxicity of 8-aminopyrimido(-4,5-c)isoquinoliequinone APIQs

      Аннотация: This book deals with the quantitative structure activity relationship study of cytotoxicity of 8-aminopyrimido(4,5-c)isoquinolinequinone. It consists of 3 chapters: Chapter one shows the important of QSAR , as a computational chemistry tool, and related it with Computer-Aided Drug Design CADD . it talks about the chemistry of quinone beside the anticancer activity of them. Chapter two explains the QSAR methodologies that were used (regression and classification). the third chapter includes results and discussion which present a good QSAR model and a mechanistic study for these compound.

Ключевые слова: Computational Chemistry, QSAR, APIQS