Antiplasmodial Activity of Croton macrostachus Extracts. Antimalarial Activity of Croton macrostachyus Extracts Against Plasmodium falciparum (D 6) and Plasmodium berghei (ANKA)

      Аннотация: Medicinal plants have been used to cure malaria and parasitic diseases for centuries. The content of this book is aimed at demonstrating the effects of Croton macrostachyus (Euphorbiaceae) extracts in vitro using chloroquine-sensitive Plasmodium falciparum (STRAIN D6) and in vivo using Plasmodium berghei (STRAIN: ANKA). Chemical analysis of the plant included extraction using methanol, ethyl acetate, butanol, and water. Chemical analysis was carried out at The University of Eastern Africa, Baraton and University of Chicago, USA. The bioassays were carried out at the Kenya Medical Research Institute. The results in this book demonstrate that there is a need to explore alternative treatments for parasitic infections like malaria from natural products that have fewer side effects where conventional medications are unavailable and inaccessible.

Ключевые слова: croton macrostachyus, plasmodium falciparum, Plasmodium berghei, extracts, in vitro, in vivo, parasitaemia, Percent Suppression of Parasitaemia