How I Manage Cancer in a Developing Country. The case of Multiple Myeloma

      Аннотация: Cancer poses a global health problem, especially in transiting countries due to rudimentary modes of diagnosis and treatment in the regions. Multiple myeloma, a haematologic malignancy that affects predominantly the bone marrow microenvironment constitutes about 1% of all cancer diagnoses. The management of Multiple myeloma (MM) could be daunting in economic-constrained settings such as those found in low-income countries of sub-Saharan Africa. Apart from late presentations of the disease, the patients are confronted with challenges of diagnosis and early care or treatment. The hallmarks are increased case complications, increased disability adjusted life years (DALY) and reduced quality adjusted life years (QALYs). This book is a comprehensive overview of the challenges encountered in the diagnosis and palliative care of MM in Nigeria; the therapeutic interventions and opportunities available to improve case ascertainment and QALYs of the sufferers in the region. It is a compilation of research studies on multiple myeloma in the region bringing to fore the strengths, weaknesses, opportunities and threats to effective management of multiple myeloma.

Ключевые слова: Cancer, Multiple Myeloma, Aetio-pathogenesis, risk assessment, Anti-myeloma agents, palliative care, risk factors, causal inference, Risk Management, DEVELOPED AND DEVELOPING COUNTRIES, challenges, diagnosis, Africa, Sub-Saharan Africa, Nigeria, Melphalan-Prednisone (MP), Bortezomib, lenalidomide, thalidomide, Bone Marrrow Plasma Cells (BMPC), Niger Delta, Survival Outcome, Chemotherapy, Risk stratification, IgA-kappa, health promotion, Health Campaign, prevention, Awareness, SWOT Analysis, Epidemiological investigation, Medical effectiveness, Strategic approaches, Health education, screening test, Policy-making, framework, quality, Middle-aged, Elderly, pharmacovigilance, Risk Management Programme