Important tools don’t forget in acute cardiotoxicity management. ECG, cardiac troponin I, GCS, MAS how can be important when you evaluate acute cardiotoxic patient

      Аннотация: This study showed that:• The majority of the studied patients (94%) survived and (6%) of the patients died. • ECG test sensitivity was 100%, specificity was 46.8%, PPV of ECG was 10.7% and NPV was 100%.• MAS score, GCS score, and serum cTnI were very highly significantly increased with death hence could be used as predictors for the mortality.• Serum CK-MB couldn’t be used as an outcome predictor.• Serum cTnI>1.0ng/ml had sensitivity 100% and specificity 89.4% and NPV 100% with excellent diagnostic characteristic (accuracy rate 96.4%).• GCS at cut off <9.5 had sensitivity 100% and specificity 77.3% and NPV 100% with excellent diagnostic characteristic (accuracy rate 92.4%).• MAS score at cut off value > 10 had corresponding sensitivity 100% and specificity 74.5% and NPV 100% with excellent diagnostic characteristic (accuracy rate 90.8%). • Performing an ECG for every patient with acute poisoning help in early recognizing the possible cardio-toxicity by simple and non-invasive tool.• The protocol of management will be the same in acute toxicity by cardiac drugs and non-cardiac toxins.

Ключевые слова: cardiotoxicity management, ecg, Cardiac troponin I, Cardiotoxicity, GCS, mAs, Patient, test, DEATH, Mortality, diagnostic characteristic, cardiovascular effects, cardiac drugs