Enhancement of Dopamine Receptor D3 Gene Expression. And Detection of Gene Mutations of Phenylalanine Hydroxylase in Phenylketonuria Patients

      Аннотация: Dopamine is a neurotransmitter hormone for pleasure and reward. It is synthesized only in the brain cells of human and animals and responsible for the regulation of behavior, mood, memory, cognitive, flexible movement, the body weight and other important functions. The Dopamine Receptor D3 (DRD3) is the most important receptor for dopamine. In this investigation, expression of DRD3 gene was studied in rabbits fed on supplemented diet of dry and fresh faba bean (Vicia faba L. Sakha 3).Our findings indicated the decisive effect of dry faba bean on increasing phenylalanine hydroxylase (PAH) levels which improve life quality of human and compound animal wealth.

Ключевые слова: Dopamine, D3 gene, gene mutations, phenylketonuria patients, diet, Health, food