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Sequencing, Finishing, Analysis in The Future. Sequencing, Finishing, Analysis in The Future Application of Next-Generation Sequencing in Medical Discovery
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Местонахождение: Алматы | Состояние экземпляра: новый |
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версия
версия
Автор: Suman Chaudhary,Anjana Singh and Peixin Huang
ISBN: 9786206147916
Год издания: 1905
Формат книги: 60×90/16 (145×215 мм)
Количество страниц: 120
Издательство: LAP LAMBERT Academic Publishing
Цена: 35503 тг
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Аннотация: Over the past few years, next-generation DNA sequencing has emerged as a new and powerful technology allowing a much more comprehensive view of biological systems at the genetic level and thus more medical discoveries. Not long ago, the Sanger method for DNA sequencing, considered as first-generation DNA sequencing, was the workhorse in the completion of the human genome project. The Sanger method was often the best choice for de novo sequencing, resequencing, genotyping, and fragment analysis. However, the high cost and low speed of the Sanger method presented a hurdle to sequence large numbers of bases as needed in the era of personalized medicine. To address these drawbacks, many companies and researchers have successfully developed "next-generation DNA sequencing" methods, i.e., any new sequencing method with lower cost and higher speed that is not based on the Sanger method. This chapter will first introduce next generation DNA sequencing technology and then synopsize its application into medical discoveries. The objective of this chapter is to pitch readers to be acquainted with next generation DNA sequencing technology.
Ключевые слова: bioinformatics, RNA, DNA